- Peripheral artery disease (PAD) is the narrowing or blockage of arteries that carry oxygen-rich blood from the heart to the limbs, head and organs. Discomfort in the leg, especially when walking, is the most common symptom of PAD.
- The primary cause of PAD is atherosclerosis, which is the buildup of cholesterol and fat (plaque) on the artery walls.
- PAD increases the risk of developing coronary heart disease, heart attack or stroke.
- If severe enough, PAD can cause gangrene (tissue death).
Peripheral artery disease (PAD) is a condition that occurs in the arteries of the circulatory system. Healthy arteries promote the steady flow of blood. If the arteries become narrowed or blocked, blood cannot get through, causing damage to tissues or organs.